About Acetaminophen

Acetaminophen  is the most common drug ingredient in America. It is found in more than 600 different medicines, including prescription and over-the-counter medicines pain relievers, fever reducers, and sleep aids as well as cough, cold, and allergy medicines.

When used as directed, acetaminophen is safe and effective. But there is a limit to how much you can take in one day. Taking more acetaminophen than directed is an overdose and can lead to liver damage. The U.S. Food and Drug Administration recommends taking no more than 4,000 mg of acetaminophen in a 24-hour period.

Follow three simple steps to use acetaminophen safely:

  1. Always read and follow the label.

    Never take more medicine than the label says. Taking more acetaminophen than directed is an overdose and can lead to liver damage.

  2. Know if your medicines contain acetaminophen.

    It is important to check the active ingredients in all of your medicines to see if they contain acetaminophen.

    • On over-the-counter medicines the word “acetaminophen” is listed on the front of the package or bottle and in the active ingredient section of the Drug Facts label.
    • On prescription labels, acetaminophen is sometimes listed as “APAP,” “acetam,” or other shortened versions of the word.
  3. Never take two medicines that contain acetaminophen at the same time.

    You can take too much acetaminophen if you use more than one medicine that contains acetaminophen at the same time.

Talk to your healthcare provider before taking acetaminophen if you drink three or more alcoholic drinks a day, if you have liver disease, or if you take warfarin. You may be at greater risk for liver damage. You should also talk to your healthcare professional if you are pregnant or breastfeeding before taking acetaminophen.

Forms of
TabletsChewable Tablets
Gel TabsLiquid
SuppositoriesDissolving Strips
Shapes of Acetaminophen:




The National Library of Medicine (NLM)

The National Library of Medicine (NLM) is the world's largest medical library. The Library offers databases and search tools to help identify and learn more about over-the-counter and prescription medicines. Visit the NLM’s DailyMed database.

What is Acetaminophen?: